Efficient synthesis of N-acyl-α-amino acids via polymer incarcerated palladium-catalyzed amidocarbonylation

被引：28

作者：

Akiyama, R ^{[1
]}

Sagae, T ^{[1
]}

Sugiura, M ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2004年 / 689卷 / 23期

基金：

日本科学技术振兴机构; 日本学术振兴会;

关键词：

amino acid; polymer-supported catalyst; amidocarbonylation;

D O I：

10.1016/j.jorganchem.2004.07.017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A novel polymer incarcerated Pd catalyst (PI Pd 7c) was synthesized from amide-containing polymer 6b, and this catalyst was shown to be effective in amidocarbonylation, which is a versatile one-pot method for the preparation of N-acyl-alpha-amino acids. The reactions proceeded smoothly with a wide variety of substrates, and no leaching of the Pd metal to the reaction mixture was detected. (C) 2004 Published by Elsevier B.V.

引用

页码：3806 / 3809

页数：4

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