Efficient synthesis of N-acyl-α-amino acids via polymer incarcerated palladium-catalyzed amidocarbonylation

被引：28

作者：

Akiyama, R ^{[1
]}

Sagae, T ^{[1
]}

Sugiura, M ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2004年 / 689卷 / 23期

基金：

日本科学技术振兴机构; 日本学术振兴会;

关键词：

amino acid; polymer-supported catalyst; amidocarbonylation;

D O I：

10.1016/j.jorganchem.2004.07.017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A novel polymer incarcerated Pd catalyst (PI Pd 7c) was synthesized from amide-containing polymer 6b, and this catalyst was shown to be effective in amidocarbonylation, which is a versatile one-pot method for the preparation of N-acyl-alpha-amino acids. The reactions proceeded smoothly with a wide variety of substrates, and no leaching of the Pd metal to the reaction mixture was detected. (C) 2004 Published by Elsevier B.V.

引用

页码：3806 / 3809

页数：4

共 32 条

[11] Beller M, 1999, ANGEW CHEM INT EDIT, V38, P1454, DOI 10.1002/(SICI)1521-3773(19990517)38:10<1454::AID-ANIE1454>3.0.CO
[12] 2-D
[13] DRAUZ K, 1999, Patent No. 10012251
[14] Microencapsulated osmium tetroxide-catalyzed asymmetric dihydroxylation of olefins in water without using organic cosolvents
Ishida, T
Akiyama, R
Kobayashi, S
[J]. ADVANCED SYNTHESIS & CATALYSIS, 2003, 345 (05) : 576 - 579
[15] Palladium on carbon encapsulated in POEPOP1500:: A resin-supported catalyst for hydrogenation reactions
Jansson, AM
Grotli, M
Halkes, KM
Meldal, M
[J]. ORGANIC LETTERS, 2002, 4 (01) : 27 - 30
[16] Catalytic asymmetric dihydroxylation of olefins using a recoverable and reusable polymer-supported osmium catalyst
Kobayashi, S
Endo, M
Nagayama, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (48) : 11229 - 11230
[17] Catalytic asymmetric dihydroxylation using phenoxyethoxymethyl-polystyrene (PEM)-Based novel microencapsulated osmium tetroxide (PEM-MC OsO4)
Kobayashi, S
Ishida, T
Akiyama, R
[J]. ORGANIC LETTERS, 2001, 3 (17) : 2649 - 2652
[18] A microencapsulated Lewis acid. A new type of polymer-supported Lewis acid catalyst of wide utility in organic synthesis
Kobayashi, S
Nagayama, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (12) : 2985 - 2986
[19] Polyurea-encapsulated palladium(II) acetate: a robust and recyclable catalyst for use in conventional and supercritical media
Ley, SV
Ramarao, C
Gordon, RS
Holmes, AB
Morrison, AJ
McConvey, IF
Shirley, IM
Smith, SC
Smith, MD
[J]. CHEMICAL COMMUNICATIONS, 2002, (10) : 1134 - 1135
[20] Microencapsulated osmium tetraoxide. A new recoverable and reusable polymer-supported osmium catalyst for dihydroxylation of olefins
Nagayama, S
Endo, M
Kobayashi, S
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (18) : 6094 - 6095

← 1 2 3 4 →