The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations

被引：10

作者：

Brada, SA ^{[1
]}

Egan, TD ^{[1
]}

Viscomi, CM ^{[1
]}

机构：

[1] Univ Utah, Med Ctr, Dept Anesthesiol, Salt Lake City, UT 84132 USA

来源：

INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA | 1998年 / 7卷 / 02期

关键词：

D O I：

10.1016/S0959-289X(98)90009-7

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We present a case in which remifentanil infusion was used to provide analgesia during epidural catheter placement in a parturient who was experiencing gnat difficulty staying motionless because of extremely painful uterine contractions. Remifentanil may provide certain advantages in this setting, including improved analgesia during the procedure, briefer residual maternal and fetal (or newborn) drug effects after the procedure, and greater technical ease of catheter placement because of decreased movement induced by pain. Pharmacokinetic simulation of the dose administered suggests that analgesic effect-site concentrations can be rapidly produced, and that these concentrations decline rapidly to clinically insignificant levels after the infusion.

引用

页码：124 / 127

页数：4

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