A novel method for the synthesis of functionalized spirocyclic oxindoles by one-pot tandem reaction of vinyl malononitriles with isatylidene malononitriles

被引：66

作者：

Babu, Thelagathoti Hari ^{[1
]}

Joseph, A. Abragam ^{[1
]}

Muralidharan, D. ^{[1
]}

Perumal, Paramasivan T. ^{[1
]}

机构：

[1] CSIR, Div Organ Chem, Cent Leather Res Inst, Madras 600020, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 06期

关键词：

Vinylogous Michael addition; One-pot tandem reaction; Spirocyclic oxindoles; PUMMERER REACTION CHEMISTRY; ASYMMETRIC DOMINO REACTIONS; TRANSFER HYDROGENATION; EFFICIENT METHOD; DERIVATIVES; CYCLIZATION; FACILE; PART;

D O I：

10.1016/j.tetlet.2009.12.082

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One-pot synthesis of novel spirocyclic oxindoles was achieved via vinylogous Michael addition of vinyl malononitriles on isatin-malononitrile adducts as the key step followed by a sequential tandem reaction. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：994 / 996

页数：3

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