The Wisconsin Card Sorting Test and the N-back test in mild cognitive impairment and elderly depression

被引：29

作者：

Borkowska, Alina ^{[1
]}

Drozdz, Wiktor ^{[1
]}

Jurkowski, Piotr ^{[2
]}

Rybakowski, Janusz K. ^{[3
]}

机构：

[1] Nicolaus Copernicus Univ Torun, Clin Neuropsychol Unit, Coll Medicum Bydgoszcz, PL-85094 Bydgoszcz, Poland

[2] Nicolaus Copernicus Univ Torun, Dept Informat & Methodol Sci, Coll Medicum Bydgoszcz, PL-85094 Bydgoszcz, Poland

[3] Poznan Univ Med Sci, Dept Adult Psychiat, Poznan, Poland

来源：

WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY | 2009年 / 10卷 / 04期

关键词：

Wisconsin Card Sorting Test; N-back test; Mild Cognitive Impairment; elderly depression; EXECUTIVE DYSFUNCTION; ALZHEIMERS-DISEASE; MODIFIED VERSION; WORKING-MEMORY;

D O I：

10.1080/15622970701557985

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The aim of this study was to assess cognitive functions in 30 non-depressed patients with mild cognitive impairment (MCI), compared with 30 age-, gender-and education-matched patients with acute depressive episode, and with 30 healthy subjects. Neuropsychological assessment included the Mini Mental State Examination (MMSE), memory tests as well as the Wisconsin Card Sorting Test (WCST) and the N-back test. Patients with MCI obtained significantly worse results on all domains of the WCST and the N-back test compared to both depressed and healthy subjects. Depressed patients showed significantly worse performance than controls on most scores. In the MCI group, no association with MMSE was found with any of WCST domains, or with reaction time in the N-back test. Three tests, WCST-P, N-back %CORR and WCST 1st CAT obtained highest ranks (>90) as predictors for differentiating between groups. The results suggest a usefulness of employing WCST and N-back tests for a neuropsychological evaluation of patients with MCI.

引用

页码：870 / 876

页数：7