Preparation and characterization of macroporous poly(2-hydroxyethyl methacrylate)-based biomaterials:: Water sorption property and in vitro blood compatibility

被引：30

作者：

Bajpai, A. K. ^{[1
]}

Kankane, Sanjana ^{[1
]}

机构：

[1] Govt Autonomous Sci Coll, Dept Chem, Bose Mem Res Lab, Jabalpur 482001, Madhya Pradesh, India

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2007年 / 104卷 / 03期

关键词：

hydrogel; interpenetrating polymer network; swelling; blood compatibility;

D O I：

10.1002/app.25580

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A semi-interpenetrating polymer network (IPN) comprising gelatin and poly(2-hydroxyethyl methacrylate-co-acrylamide) was prepared and characterized by FTIR, environmental scanning electron microscopy (ESEM) and differential scanning calorimetry (DSC) techniques. The water sorption potential of the prepared semi-IPNs was investigated for varying chemical architecture of the IPN, and experimental conditions such as pH, temperature and ionic strength of the swelling media. The semi-IPNs were also judged for in vitro blood compatibility by performing blood clot, percent hemolysis, protein adsorption and platelet adhesion tests. (c) 2007 Wiley Periodicals, Inc.

引用

页码：1559 / 1571

页数：13

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