Unexpected nuclear formylation and acetylation of some nitroanilines with dimethyl sulfoxide in the presence of a strong base

被引：18

作者：

Kawakami, T ^{[1
]}

Suzuki, H ^{[1
]}

机构：

[1] Kwansei Gakuin Univ, Sch Sci, Dept Chem, Nishinomiya, Hyogo 6628501, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 36期

关键词：

acylation; sulfoxides; nitro compounds; arenes; carbanions;

D O I：

10.1016/S0040-4039(00)01215-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

When treated with a strong base such as (KOBu)-Bu-t or NaH in dimethyl sulfoxide at room temperature, 2,4-dinitro-, 2-cyano-4-nitro- and 4-cyano-2-nitroanilines were found to undergo regiospecific acylation at the 3-position to afford the corresponding 3-formyl or 3-acetyl derivatives in fair to moderate yields. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7093 / 7096

页数：4

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