Development of the micro- and nanoelectrodes for cells investigation

被引：10

作者：

Kleps, Irina ^{[1
]}

Miu, Mihaela ^{[1
]}

Craciunoiu, Florea ^{[1
]}

Simion, Monica ^{[1
]}

机构：

[1] IMT Bucharest, Natl Inst Res & Dev Microtechnol, Bucharest 077190, Romania

来源：

MICROELECTRONIC ENGINEERING | 2007年 / 84卷 / 5-8期

关键词：

nanoelectrodes; cells; lab-on-a-chip; biosensors; technological development;

D O I：

10.1016/j.mee.2007.01.268

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This research is directed to the developing of a new silicon microchip technology to investigate the structure and dynamics of the cell-semiconductor interface subjected to various chemical (nutrients, hormones, drug solution, etc.) or physical (change in temperature, light, electric field, etc.) stimuli. The proposed fabrication technology of the sensing element on silicon can be adjusted for a wide range of applications, as follows: (a) nanoelectrode array (NEA) as working electrode in an electrochemical cell on a chip and (b) a single nanoelectrode (NE) situated in A microfluidic system for the electrical measurements of the cellular processes when a direct contact of cell membranes with the semiconductor chip. (c) 2007 Published by Elsevier B.V.

引用

页码：1744 / 1748

页数：5

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