Study on cytotoxic oxygenated desmosterols isolated from the red alga Galaxaura marginata

被引:41
作者
Sheu, JH
Huang, SY
Wang, GH
Duh, CY
机构
[1] Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung
来源
JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 09期
关键词
D O I
10.1021/np9701844
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Four novel oxygenated desmosterols, 24 xi-hydroperoxy-6 beta-hydroxycholesta-4,25-dien-3-one (1), 25-hydroperoxy-6 beta-hydroxycholesta-4,23(E)-dien-3-one (2), 24 xi-hydroperoxycholesta-4,25-diene-3,6-dione (3), and 25-hydroperoxycholesta-4,23(E)-diene-3,6-dione (4) were isolated from the marine red alga Galaxaura marginata. Steroids 1-4 and three synthetic oxygenated desmosterols 5-7 were shown to exhibit significant cytotoxicity against several cancer cell lines.
引用
收藏
页码:900 / 903
页数:4
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