Study on cytotoxic oxygenated desmosterols isolated from the red alga Galaxaura marginata

被引：41

作者：

Sheu, JH

Huang, SY

Wang, GH

Duh, CY

机构：

[1] Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 09期

关键词：

D O I：

10.1021/np9701844

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four novel oxygenated desmosterols, 24 xi-hydroperoxy-6 beta-hydroxycholesta-4,25-dien-3-one (1), 25-hydroperoxy-6 beta-hydroxycholesta-4,23(E)-dien-3-one (2), 24 xi-hydroperoxycholesta-4,25-diene-3,6-dione (3), and 25-hydroperoxycholesta-4,23(E)-diene-3,6-dione (4) were isolated from the marine red alga Galaxaura marginata. Steroids 1-4 and three synthetic oxygenated desmosterols 5-7 were shown to exhibit significant cytotoxicity against several cancer cell lines.

引用

页码：900 / 903

页数：4

共 14 条

[11] 7-OXOSTEROLS, 7-ALPHA-HYDROXYSTEROLS AND 7-BETA-HYDROXYSTEROLS FROM EUPHORBIA-FISCHERIANA [J].