Insulin resistance, premature adrenarche, and a risk of the polycystic ovary syndrome (PCOS)

被引：32

作者：

Ibáñez, L ^{[1
]}

Potau, N

Carrascosa, A

机构：

[1] Univ Autonoma Barcelona, Hosp Maternoinfantil Vall dHebron, Adolescent & Endocrine Unit, E-08193 Barcelona, Spain

[2] Univ Autonoma Barcelona, Hosp Maternoinfantil Vall dHebron, Hormonal Lab, E-08193 Barcelona, Spain

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1998年 / 9卷 / 02期

关键词：

D O I：

10.1016/S1043-2760(98)00014-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Timing of puberty and final height are usually normal in girls with a history of premature adrenarche. However, these patients show an increased frequency of ovarian hyperandrogenism, hyperinsulinism and dyslipemia at adolescence. The hyperinsulinemia and lipid disturbances can often be detected in the prepubertal period, recommending long-term follow-up of these patients into adulthood.

引用

页码：72 / 77

页数：6

共 70 条

[1] INSULIN RESISTANCE OF PUBERTY - A DEFECT RESTRICTED TO PERIPHERAL GLUCOSE-METABOLISM [J].

AMIEL, SA ;

CAPRIO, S ;

SHERWIN, RS ;

PLEWE, G ;

HAYMOND, MW ;

TAMBORLANE, WV .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1991, 72 (02) :277-282

[2] METABOLIC FEATURES OF POLYCYSTIC-OVARY-SYNDROME ARE FOUND IN ADOLESCENT GIRLS WITH HYPERANDROGENISM [J].

APTER, D ;

BUTZOW, T ;

LAUGHLIN, GA ;

YEN, SSC .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (10) :2966-2973

[3] Insulin sensitivity, lipids, and body composition in childhood: Is ''syndrome X'' present? [J].

Arslanian, S ;

Suprasongsin, C .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (03) :1058-1062

[4] POLYCYSTIC OVARIAN DISEASE [J].

BARBIERI, RL .

ANNUAL REVIEW OF MEDICINE, 1991, 42 :199-204

[5] INSULIN STIMULATES ANDROGEN ACCUMULATION IN INCUBATIONS OF OVARIAN STROMA OBTAINED FROM WOMEN WITH HYPERANDROGENISM [J].

BARBIERI, RL ;

MAKRIS, A ;

RANDALL, RW ;

DANIELS, G ;

KISTNER, RW ;

RYAN, KJ .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 62 (05) :904-910

[6] PITUITARY OVARIAN RESPONSES TO NAFARELIN TESTING IN THE POLYCYSTIC OVARY SYNDROME [J].

BARNES, RB ;

ROSENFIELD, RL ;

BURSTEIN, S ;

EHRMANN, DA .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (09) :559-565

[7]

BIRSDALL MA, 1997, ANN INTERN MED, V126, P32

[8] INCREASED INSULIN-SECRETION IN PUBERTY - A COMPENSATORY RESPONSE TO REDUCTIONS IN INSULIN SENSITIVITY [J].

CAPRIO, S ;

PLEWE, G ;

DIAMOND, MP ;

SIMONSON, DC ;

BOULWARE, SD ;

SHERWIN, RS ;

TAMBORLANE, WV .

JOURNAL OF PEDIATRICS, 1989, 114 (06) :963-967

[9] INSULIN-LIKE GROWTH FACTOR-I AND INSULIN POTENTIATE LUTEINIZING HORMONE-INDUCED ANDROGEN SYNTHESIS BY RAT OVARIAN THECAL-INTERSTITIAL CELLS [J].

CARA, JF ;

ROSENFIELD, RL .

ENDOCRINOLOGY, 1988, 123 (02) :733-739

[10] Cross-sectional growth study of the child and adolescent population of Catalonia (Spain) [J].

delaPuente, ML ;

Canela, J ;

Alvarez, J ;

Salleras, L ;

VicensCalvet, E .

ANNALS OF HUMAN BIOLOGY, 1997, 24 (05) :435-452

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