Viral mechanisms of immune evasion

被引:38
作者
Alcami, A
Koszinowski, UH
机构
[1] Univ Cambridge, Dept Pathol, Div Virol, Cambridge CB2 1QP, England
[2] Univ Munich, Gene Ctr, Dept Virol, Max Von Pettenkofer Inst, D-81377 Munich, Germany
来源
MOLECULAR MEDICINE TODAY | 2000年 / 6卷 / 09期
基金
英国惠康基金;
关键词
D O I
10.1016/S1357-4310(00)01775-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral pathogenesis, and could lead to new anti-viral strategies and the ability to exploit viral functions as tools in medicine.
引用
收藏
页码:365 / 372
页数:10
相关论文
共 50 条
[1]   HIV-1 Tat protein mimicry of chemokines [J].
Albini, A ;
Ferrini, S ;
Benelli, R ;
Sforzini, S ;
Giunciuglio, D ;
Aluigi, MG ;
Proudfoot, AEI ;
Alouani, S ;
Wells, TNC ;
Mariani, G ;
Rabin, RL ;
Farber, JM ;
Noonan, DM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (22) :13153-13158
[2]   Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors [J].
Alcamí, A ;
Khanna, A ;
Paul, NL ;
Smith, GL .
JOURNAL OF GENERAL VIROLOGY, 1999, 80 :949-959
[3]   Poxviruses:: Capturing cytokines and chemokines [J].
Alcamí, A ;
Symons, JA ;
Khanna, A ;
Smith, GL .
SEMINARS IN VIROLOGY, 1998, 8 (05) :419-427
[4]   Deletion of a CD2-like gene, 8-DR, from African swine fever virus affects viral infection in domestic swine [J].
Borca, MV ;
Carrillo, C ;
Zsak, L ;
Laegreid, WW ;
Kutish, GF ;
Neilan, JG ;
Burrage, TG ;
Rock, DL .
JOURNAL OF VIROLOGY, 1998, 72 (04) :2881-2889
[5]   A poxvirus protein that binds to and inactivates IL-18, and inhibits NK cell response [J].
Born, TL ;
Morrison, LA ;
Esteban, DJ ;
VandenBos, T ;
Thebeau, LG ;
Chen, NH ;
Spriggs, MK ;
Sims, JE ;
Buller, RML .
JOURNAL OF IMMUNOLOGY, 2000, 164 (06) :3246-3254
[6]   Ectromelia virus virulence factor p28 acts upstream of caspase-3 in response to UV light-induced apoptosis [J].
Brick, DJ ;
Burke, RD ;
Minkley, AA ;
Upton, C .
JOURNAL OF GENERAL VIROLOGY, 2000, 81 :1087-1097
[7]   The equine herpesvirus 2 E1 open reading frame encodes a functional chemokine receptor [J].
Camarda, G ;
Spinetti, G ;
Bernardini, G ;
Mair, C ;
Davis-Poynter, N ;
Capogrossi, MC ;
Napolitano, M .
JOURNAL OF VIROLOGY, 1999, 73 (12) :9843-9848
[8]   Structure of a soluble secreted chemokine inhibitor vCCl (p35) from cowpox virus [J].
Carfi, A ;
Smith, CA ;
Smolak, PJ ;
McGrew, J ;
Wiley, DC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12379-12383
[9]   Human cytomegalovirus strain-dependent changes in NK cell recognition of infected fibroblasts [J].
Cerboni, C ;
Mousavi-Jazi, M ;
Linde, A ;
Söderström, K ;
Brytting, M ;
Wahren, B ;
Kärre, K ;
Carbone, E .
JOURNAL OF IMMUNOLOGY, 2000, 164 (09) :4775-4782
[10]   Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis [J].
Coscoy, L ;
Ganem, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (14) :8051-8056