Emerging targets for the development of novel antifungal therapeutics

被引：74

作者：

Groll, AH ^{[1
]}

De Lucca, AJ

Walsh, TJ

机构：

[1] NCI, Immunocompromised Host Sect, Pediat Oncol Branch, NIH, Bethesda, MD 20892 USA

[2] ARS, So Reg Res Ctr, USDA, New Orleans, LA USA

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0966-842X(97)01206-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.

引用

页码：117 / 124

页数：8

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