Zinc-Catalyzed Reduction of Amides: Unprecedented Selectivity and Functional Group Tolerance

被引：332

作者：

Das, Shoubhik ^{[1
]}

Addis, Daniele ^{[1
]}

Zhou, Shaolin ^{[1
]}

Junge, Kathrin ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 06期

关键词：

TERTIARY-AMINES; SELF-ENCAPSULATION; CARBONYL-COMPOUNDS; SILANE REDUCTION; HYDROSILYLATION; KETONES; POLYMETHYLHYDROSILOXANE; CARBOXAMIDES; EFFICIENT; HYDROSILATION;

D O I：

10.1021/ja910083q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel zinc-catalyzed reduction of tertiary amides was developed. This system shows remarkable chemoselectivity and substrate scope tolerating ester, ether, nitro, cyano, azo, and keto substituents

引用

页码：1770 / +

页数：4

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