Dihydroisocoumarins and a tetralone from Cytospora eucalypticola

被引：88

作者：

Kokubun, T ^{[1
]}

Veitch, NC ^{[1
]}

Bridge, PD ^{[1
]}

Simmonds, MSJ ^{[1
]}

机构：

[1] Royal Bot Gardens, Richmond TW9 3AB, Surrey, England

来源：

PHYTOCHEMISTRY | 2003年 / 62卷 / 05期

关键词：

Cytospora eucalypticola; isocoumarins; polyketides; anti-microbial activity; anti-insect activity;

D O I：

10.1016/S0031-9422(02)00606-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two dihydroisocoumarins, 3,5-dimethyl-8-hydroxy-7-methoxy-3,4-dihydroisocoumarin and 3,5-dimethyl-8-methoxy-3,4-dihydroisocoumarin were isolated from a culture filtrate of Cytospora eucalypticola, together with three known dihydroisocoumarins and a tetralone derivative. Their structures were determined by spectroscopic methods. These isocoumarins are mildly antifungal, and antibacterial towards gram positive bacteria. A known compound, 5-hydroxymethylmellein, showed mild antifeedant activity towards Spodoptera littoralis. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：779 / 782

页数：4

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