Experience-dependent rescaling of entorhinal grids

被引：379

作者：

Barry, Caswell

Hayman, Robin

Burgess, Neil

Jeffery, Kathryn J.

机构：

[1] UCL, Inst Cognit Neurosci, London WC1N 3AR, England

[2] UCL, Dept Anat, London WC1E 6BT, England

[3] UCL, Dept Psychol, London WC1H 0AP, England

来源：

NATURE NEUROSCIENCE | 2007年 / 10卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1038/nn1905

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.

引用

页码：682 / 684

页数：3

共 16 条

[11] Long-term plasticity in hippocampal place-cell representation of environmental geometry [J].