How structurally normal are human atria in patients with atrial fibrillation?

被引：33

作者：

Becker, AE ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Cardiovasc Pathol, NL-1473 PP Warder, Netherlands

来源：

HEART RHYTHM | 2004年 / 1卷 / 05期

关键词：

atrial fibrillation; atrial arrhythmias; atrial fibrosis; atrial infarction; atrial myocardium; terminal crest; Bachmann's bundle; pulmonary veins;

D O I：

10.1016/j.hrthm.2004.09.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial myocardium in humans shows structural changes that increase with aging. The most conspicuous are fibro-fatty replacement and patchy replacement fibrosis. The present study reveals that these structural changes are more extensive in hearts of patients with paroxysmal atrial fibrillation (AF) than in "no AF' hearts. The changes involve the myocardial sleeves on pulmonary veins and sites of rapid conduction, such as the terminal crest and Bachmann's bundle. These structural changes should be taken into consideration as potential substrates for initiation and maintenance of atrial arrhythmias. (C) 2004 Heart Rhythm Society. All rights reserved.

引用

页码：627 / 631

页数：5

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