Calcium binding and conformational response in EF-hand proteins

被引：394

作者：

Ikura, M

机构：

[1] UNIV TORONTO,DEPT MED BIOPHYS,TORONTO,ON M5G 2M9,CANADA

[2] UNIV TSUKUBA,CTR TSUKUBA ADV RES ALLIANCE,TSUKUBA,IBARAKI 305,JAPAN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 01期

关键词：

D O I：

10.1016/0968-0004(96)80879-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

EF-hand proteins undergo conformational changes upon binding of Ca2+. This event is a crucial step in many Ca2+-dependent cellular processes. Recent advances in the three-dimensional structural analysis of various EF-hand proteins have led to new insights into the structure and functional relationship of this large family of Ca2+-binding proteins.

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页码：14 / 17

页数：4

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