HPTLC determination of caffeine in stimulant herbal products and power drinks

被引：43

作者：

Abourashed, EA ^{[1
]}

Mossa, JS ^{[1
]}

机构：

[1] King Saud Univ, Coll Pharm, Dept Pharmacognosy, Riyadh 11451, Saudi Arabia

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2004年 / 36卷 / 03期

关键词：

HPTLC; caffeine; dietary supplements; herbal products; energy drinks;

D O I：

10.1016/j.jpba.2004.06.029

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The caffeine content of selected herbal products and energy drinks available in the Saudi market was determined by HPTLC-UV densitometric analysis. Pre-coated HPTLC silica gel plates (20cm x 10cm) were used for the analysis. The solvent system consisted of ethyl acetate-methanol (85:15, v/v), and caffeine was detected at 275 nm. The developed method was validated for specificity, repeatability (C.V. < 5%). recovery (98.90 +/- 3.46). and accuracy (99.84 +/- 2.87). The levels of caffeine were 4.76-13.29% (w/w) and 0.011-0.032% (w/v), for the herbal products and the energy drinks, respectively. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：617 / 620

页数：4

共 12 条

[1] [Anonymous], 1999, LAVOISIER PARIS
[2] Simultaneous determination of some multicomponent dosage forms by quantitative thin layer chromatography densitometric method
Bebawy, LI
El-Kousy, NM
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 20 (04) : 663 - 670
[3] Two new spectrophotometric approaches to the multicomponent analysis of the acetaminophen and caffeine in tablets by classical least-squares and principal component regression techniques
Dinç, E
Baleanu, D
[J]. FARMACO, 2002, 57 (01): : 33 - 37
[4] Validation in pharmaceutical analysis. Part I: An integrated approach
Ermer, J
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2001, 24 (5-6) : 755 - 767
[5] Ferenczi-Fodor K, 2001, J AOAC INT, V84, P1265
[6] Simultaneous spectrophotometric determination of phenilpropanolamine HCL, caffeine and diazepam in tablets
Ferreyra, CF
Ortiz, CS
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 29 (05) : 811 - 818
[7] *INT FOOD INF COUN, 1998, 39712 INT FOOD INF C
[8] Estimation of black tea quality by analysis of chemical composition and colour difference of tea infusions
Liang, YR
Lu, JL
Zhang, LY
Wu, S
Wu, Y
[J]. FOOD CHEMISTRY, 2003, 80 (02) : 283 - 290
[9] Planar chromatography at the turn of the century
Poole, CF
[J]. JOURNAL OF CHROMATOGRAPHY A, 1999, 856 (1-2) : 399 - 427
[10] Sample purification for the analysis of caffeine in tobacco by gas chromatography mass spectrometry
Song, SQ
Ashley, DL
[J]. JOURNAL OF CHROMATOGRAPHY A, 1998, 814 (1-2) : 171 - 180

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