The assignment of absolute configurations by NMR of arylmethoxyacetate derivatives:: is this methodology being correctly used?

被引：74

作者：

Seco, JM ^{[1
]}

Quiñoá, E ^{[1
]}

Riguera, R ^{[1
]}

机构：

[1] Univ Santiago de Compostela, Fac Quim, Dept Quim Organ, Santiago De Compostela 15706, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 13期

关键词：

D O I：

10.1016/S0957-4166(00)00228-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Examples in which Mosher's method does not allow a safe configurational assignment of absolute configuration are presented. This situation occurs when: (a) L-1 and L-2 show identical signs of Delta delta(SR); (b) when both positive and negative Delta delta(SR) values coexist for the same substituent; (c) only NMR data from one substituent of L-1 or L-2 is available; and (d) when polyalcohols are treated like monoalcohols. The requirements for the correct application of this method are discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2781 / 2791

页数：11

共 30 条

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