When gene marriages don't work out: divorce by subfunctionalization

被引：123

作者：

Cusack, Brian P. ^{[1
]}

Wolfe, Kenneth H. ^{[1
]}

机构：

[1] Univ Dublin Trinity Coll, Smurfit Inst Genet, Dublin 2, Ireland

来源：

TRENDS IN GENETICS | 2007年 / 23卷 / 06期

关键词：

D O I：

10.1016/j.tig.2007.03.010

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We describe how a bifunctional gene, encoding two proteins by alternative splicing, arose when the chloroplast gene RPL32 integrated into an intron of the nuclear gene SODcp in an ancestor of mangrove and poplar trees. Mangrove retains the alternatively spliced chimeric gene, but in poplar it underwent duplication and complete subfunctionalization, through complementary structural degeneration, to re-form separate RPL32 and SODcp genes.

引用

页码：270 / 272

页数：3

共 17 条

[1]

Altschmied J, 2002, GENETICS, V161, P259

[2] Genome duplication, subfunction partitioning, and lineage divergence:: Sox9 in stickleback and zebrafish [J].

Cresko, WA ;

Yan, YL ;

Baltrus, DA ;

Amores, A ;

Singer, A ;

Rodríguez-Marí, A ;

Postlethwait, JH .

DEVELOPMENTAL DYNAMICS, 2003, 228 (03) :480-489

[3] Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes [J].

de Souza, FSJ ;

Bumaschny, VF ;

Low, MJ ;

Rubinstein, M .

MOLECULAR BIOLOGY AND EVOLUTION, 2005, 22 (12) :2417-2427

[4] Predicting subcellular localization of proteins based on their N-terminal amino acid sequence [J].

Emanuelsson, O ;

Nielsen, H ;

Brunak, S ;

von Heijne, G .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 300 (04) :1005-1016

[5]

Force A, 1999, GENETICS, V151, P1531

[6] Divergence of spatial gene expression profiles following species-specific gene duplications in human and mouse [J].

Huminiecki, L ;

Wolfe, KH .

GENOME RESEARCH, 2004, 14 (10A) :1870-1879

[7] Evolution of nitric oxide synthase regulatory genes by DNA inversion [J].

Korneev, S ;

O'Shea, M .

MOLECULAR BIOLOGY AND EVOLUTION, 2002, 19 (08) :1228-1233

[8]

Lynch M, 2000, GENETICS, V154, P459

[9]

Lynch Michael, 2004, P33

[10] Sequencing and analysis of 14,842 expressed sequence tags of burma mangrove, Bruguiera gymnorrhiza [J].

Miyama, Masashi ;

Shimizu, Hidetsugu ;

Sugiyama, Masahide ;

Hanagata, Nobutaka .

PLANT SCIENCE, 2006, 171 (02) :234-241

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