Molecular aspects of steroidogenic factor 1 (SF-1)

被引：121

作者：

Hoivik, Erling A. ^{[1
]}

Lewis, Aurelia E. ^{[1
]}

Aumo, Linda ^{[1
]}

Bakke, Marit ^{[1
]}

机构：

[1] Univ Bergen, Dept Biomed, N-5009 Bergen, Norway

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2010年 / 315卷 / 1-2期

关键词：

Steroidogenic factor 1; SF1; SF-1; NR5A1; Ad4BP; FTZ-F1; Steroidogenesis; ORPHAN NUCLEAR RECEPTOR; VENTROMEDIAL HYPOTHALAMIC NUCLEUS; ADRENAL HYPOPLASIA CONGENITA; ACUTE REGULATORY PROTEIN; MULLERIAN-INHIBITING SUBSTANCE; HYDROXYLASE GENE-EXPRESSION; DNA-BINDING DOMAIN; MOUSE FTZ-F1 GENE; WILMS-TUMOR; FACTOR-I;

D O I：

10.1016/j.mce.2009.07.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Steroidogenic factor 1 (SF-1, also called Ad4BP and NR5A1) is a nuclear receptor with critical roles in steroidogenic tissues, as well as in the brain and pituitary. In particular, SF-1 has emerged as an essential regulator of adrenal and gonadal functions and development. In the last few years, our knowledge on SF-1 has increased considerably at all levels, from the gene to the protein, and on its specific roles in different physiological processes. In this review, we discuss the current understanding on SF-1 with focus on the parameters that control the transcriptional capacity of SF-1 and the mechanisms that ensure proper stage and tissue-specific expression of the gene encoding SF-1. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

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页码：27 / 39

页数：13

相关论文

共 205 条

[51] Mechanism of action of ACTH: Beyond cAMP [J].

Gallo-Payet, N ;

Payet, MD .

MICROSCOPY RESEARCH AND TECHNIQUE, 2003, 61 (03) :275-287

[52] Regulation of Niemann-Pick C1 gene expression by the 3′5′-cyclic adenosine monophosphate pathway in steroidogenic cells [J].

Gevry, NY ;

Lalli, E ;

Sassone-Corsi, P ;

Murphy, BD .

MOLECULAR ENDOCRINOLOGY, 2003, 17 (04) :704-715

[53]

Giuili G, 1997, DEVELOPMENT, V124, P1799

[54] Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex [J].

Gummow, Brian M. ;

Scheys, Joshua O. ;

Cancelli, Victoria R. ;

Hammer, Gary D. .

MOLECULAR ENDOCRINOLOGY, 2006, 20 (11) :2711-2723

[55]

GUO IC, 2007, J BIOMED SCI

[56] EXPRESSION OF DAX-1, THE GENE RESPONSIBLE FOR X-LINKED ADRENAL HYPOPLASIA CONGENITA AND HYPOGONADOTROPIC HYPOGONADISM, IN THE HYPOTHALAMIC-PITUITARY-ADRENAL GONADAL AXIS [J].

GUO, WW ;

BURRIS, TP ;

MCCABE, ERB .

BIOCHEMICAL AND MOLECULAR MEDICINE, 1995, 56 (01) :8-13

[57] Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1 [J].

Halvorson, LM ;

Kaiser, UB ;

Chin, WW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (12) :6645-6650

[58] Minireview: Transcriptional regulation of adrenocortical development [J].

Hammer, GD ;

Parker, KL ;

Schimmer, BP .

ENDOCRINOLOGY, 2005, 146 (03) :1018-1024

[59] Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: Integration of hormone signaling in reproduction and stress [J].

Hammer, GD ;

Krylova, I ;

Zhang, YX ;

Darimont, BD ;

Simpson, K ;

Weigel, NL ;

Ingraham, HA .

MOLECULAR CELL, 1999, 3 (04) :521-526

[60] Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination [J].

Hanley, NA ;

Ball, SG ;

Clement-Jones, M ;

Hagan, DM ;

Strachan, T ;

Lindsay, S ;

Robson, S ;

Ostrer, H ;

Parker, KL ;

Wilson, DI .

MECHANISMS OF DEVELOPMENT, 1999, 87 (1-2) :175-180

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