The restriction point and control of cell proliferation

被引：205

作者：

PlanasSilva, MD ^{[1
]}

Weinberg, RA ^{[1
]}

机构：

[1] MIT,DEPT BIOL,CAMBRIDGE,MA 02142

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 06期

关键词：

D O I：

10.1016/S0955-0674(97)80076-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Research over the past two decades has defined a window of time in the early/mid G(1) phase of the cell cycle during which mammalian cells are responsive to extracellular signals. Recent evidence indicates that this period ends with the phosphorylation of the retinoblastoma protein, enabling the cells to pass through the restriction point al the end of mid G(1) phase and to commit to completing the remaining phases of the growth cycle.

引用

收藏

页码：768 / 772

页数：5

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