Convenient synthesis of functionalized terphenyls

被引：21

作者：

Greenfield, AA ^{[1
]}

Butera, JA ^{[1
]}

Caufield, CE ^{[1
]}

机构：

[1] Wyeth Ayerst Res, Chem Sci, Princeton, NJ 08543 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 13期

关键词：

Suzuki reaction; terphenyl compounds; tetrapropylammonium; perruthenate oxidation;

D O I：

10.1016/S0040-4039(03)00333-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthetic methodology amenable for rapid synthesis of differentially functionalized terphenyls is described. Orthogonality requirements for the incorporation of phenoxy acetic acid and carboxamide function have been satisfied by utilization of hydroxyethoxy group as a precursor of the acid. Highly efficient and universal procedures have been developed for acid and amide formation. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：2729 / 2732

页数：4