Bioavailability of praziquantel increases with concomitant administration of food

被引：74

作者：

Castro, N

Medina, R

Sotelo, J

Jung, H

机构：

[1] Inst Nacl Neurol & Neurocirugia, Mexico City 14269, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Mexico City 04510, DF, Mexico

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 10期

关键词：

D O I：

10.1128/AAC.44.10.2903-2904.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

引用

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页码：2903 / 2904

页数：2

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