Crystal structure of ciprofloxacin hydrochloride 1.34-hydrate

被引:34
作者
Turel, I [1 ]
Golobic, A [1 ]
机构
[1] Univ Ljubljana, Fac Chem & Chem Technol, Ljubljana 1000, Slovenia
关键词
D O I
10.2116/analsci.19.329
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Ciprofloxacin belongs to a family of quinolone antibacterial agents. The crystal structure of ciprofloxacin hydrochloride 1.34-hydrate was determined. Most of the bond lengths and angles of the ciprolloxacin cation are very similar to those of ciprofloxacin hexahydrate, which appears in the zwitterionic form. The exceptions are the carbon-oxygen bond distances in the carboxylic group, since in the title compound this group is not deprotonated. Various inter- and intramolecular hydrogen bonds were found in the molecule and are described.
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页码:329 / 330
页数:2
相关论文
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