Identification of two novel peptides from the central nervous system of the desert locust, Schistocerca gregaria

被引:24
作者
Veelaert, D [1 ]
Schoofs, L [1 ]
Verhaert, P [1 ]
De Loof, A [1 ]
机构
[1] Catholic Univ Louvain, Inst Zool, Lab Dev Biol & Mol Biol, B-3000 Louvain, Belgium
关键词
D O I
10.1006/bbrc.1997.7843
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
From an acid methanolic extract of about 7000 brains of the desert locust (Schistocerca gregaria) two novel neuropeptides, schistomyotropin-1 (Scg-MT-1) and schistomyotropin-2! (Scg-MT-2), were isolated and identified. Their primary structures are GAAPAAQFSPRLamide (Scg-MT-1) and TSSLFPHPRLamide (Scg-MT-2). Scg-MT-1 belongs to the locustamyotropin family characterized by its FXPRLamide C-terminus. Scg-MT-2 has a similar carboxyl end with the F-residue one position further away hom the C-terminus. This may account for its being 10 times less active then Scg-MT-1 in stimulating cockroach hindgut motility. (C) 1997 Academic Press.
引用
收藏
页码:530 / 534
页数:5
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