Molecular replacement with MOLREP

被引：3159

作者：

Vagin, Alexei ^{[1
]}

Teplyakov, Alexei ^{[2
]}

机构：

[1] Univ York, Struct Biol Lab, York YO10 5YW, N Yorkshire, England

[2] Univ Maryland, Inst Biotechnol, Rockville, MD 20850 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2010年 / 66卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

TRANSLATION FUNCTION; PIPELINE; CRYSTALLOGRAPHY; SOFTWARE; PROGRAM; SEARCH; SUITE;

D O I：

10.1107/S0907444909042589

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

MOLREP is an automated program for molecular replacement that utilizes a number of original approaches to rotational and translational search and data preparation. Since the first publication describing the program, MOLREP has acquired a variety of features that include weighting of the X-ray data and search models, multi-copy search, fitting the model into electron density, structural superposition of two models and rigid-body refinement. The program can run in a fully automatic mode using optimized parameters calculated from the input data.

引用

页码：22 / 25

页数：4

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