Enlarged cavum septi pellucidi in patients with schizophrenia: Clinical and cognitive correlates

被引：44

作者：

Nopoulos, P ^{[1
]}

Krie, A ^{[1
]}

Andreasen, NC ^{[1
]}

机构：

[1] Univ Iowa, Coll Med, Dept Psychiat, Mental Hlth Clin Res Ctr, Iowa City, IA 52242 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1176/appi.neuropsych.12.3.344

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Enlarged cavum septi pellucidi (CSP) is a neurodevelopmental anomaly that hers been associated with schizophrenia. This study was designed to evaluate, in patients with schizophrenia, the relationship between the severity of this anomaly and measures of symptom and cognitive skills. Three groups weve used: patients with large CSP (n = 14), patients without large CSP (n = 14), and healthy control subjects (n = 24). In patients with large CSP, a significant, inverse relationship was found between size of CSP and measures of cognitive deficit. Thus, the greater the size of the anomaly, the greater the cognitive deficit. No relationship was found between severity of CSP and symptom measures.

引用

页码：344 / 349

页数：6

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