Growth deficits and attention-deficit/hyperactivity disorder revisited: Impact of gender, development, and treatment

被引:89
作者
Biederman, J
Faraone, SV
Monuteaux, MC
Plunkett, EA
Gifford, J
Spencer, T
机构
[1] Massachusetts Gen Hosp, Dept Psychiat, Pediat Psychopharmacol Unit, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
关键词
ADHD; growth; stimulants;
D O I
10.1542/peds.111.5.1010
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective. Although the relationship between putative growth deficits and attention-deficit/hyperactivity disorder (ADHD) has been examined in boys, this issue has not been evaluated in girls. Methods. Height and weight were examined in 124 female ADHD children and 116 female controls using age and parental height corrections, attending to issues of pubertal stage and treatment. Also, we examined the interaction between ADHD status and gender on growth outcomes using data from 124 ADHD and 109 control males. Results. The ADHD-growth association was not moderated by gender. No deficits in age-adjusted height or age and height-adjusted weight were detected in ADHD girls. Also, we found no association between growth measurements and psychotropic treatment, malnutrition, short stature, pubertal development, family history of ADHD, or psychiatric comorbidity, except for major depression: ADHD girls with major depression were on average 7.6 kg heavier than ADHD girls without depression, adjusting for age and height. Conclusions. No growth deficits appear to be associated with ADHD or its treatment in females. These findings add to a growing literature supporting the notion that stimulant treatment does not have an adverse impact on ADHD children's growth and development.
引用
收藏
页码:1010 / 1016
页数:7
相关论文
共 51 条
[21]   PROLACTIN, GROWTH-HORMONE AND GROWTH-RESPONSES IN BOYS WITH ATTENTION DEFICIT DISORDER AND HYPERACTIVITY TREATED WITH METHYLPHENIDATE [J].
GREENHILL, LL ;
PUIGANTICH, J ;
NOVACENKO, H ;
SOLOMON, M ;
ANGHERN, C ;
FLOREA, J ;
GOETZ, R ;
FISCINA, B ;
SACHAR, EJ .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1984, 23 (01) :58-67
[22]  
GROSS MD, 1976, PEDIATRICS, V58, P423
[23]   PHYSICAL GROWTH - NATIONAL-CENTER-FOR-HEALTH-STATISTICS PERCENTILES [J].
HAMILL, PVV ;
DRIZD, TA ;
JOHNSON, CL ;
REED, RB ;
ROCHE, AF ;
MOORE, WM .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1979, 32 (03) :607-629
[24]  
Hollingshead AB, 1975, 4 FACTOR INDEX SOCIA
[25]  
KALACHNIK JE, 1982, DEV MED CHILD NEUROL, V70, P987
[26]  
KLEIN RG, 1988, ARCH GEN PSYCHIAT, V45, P1127
[27]  
KLEIN RG, 1988, ARCH GEN PSYCHIAT, V45, P1131
[28]  
Kuczmarski RJ., 2002, Vital Health Stat, V11, P1
[29]  
LONEY J, 1981, Psychopharmacology Bulletin, V17, P132