Objective: To determine the self-reported prevalence of domestic violence in South Australian adults and to examine the associated risk factors, demographic factors and related health issues using computer-aided telephone interviewing (CATI) methodology. Sample: A representative random sample of South Australian adults aged 18 years and over selected from the Electronic White Pages. Overall, 6,004 interviews were completed (73.1% response rate). Results: In total, 17.8% of adults in South Australia reported some form of domestic violence by a current or an ex-partner. Demographic factors such as low household income, unemployment or part-time employment and health variables such as poor to fair self-reported health status and alcohol abuse problems were found to have a significant relationship with domestic violence. Conclusions: Approximately one in five South Australian adults report physical and emotional abuse from current or ex-partners, of whom the majority are women who are separated, divorced or never married and on lower incomes. Telephone interviewing is a cost-effective method of identifying prevalence estimates of domestic violence when compared with data collection by way of police reports or hospital emergency statistics. Implications: Domestic violence is a serious public health concern often 'hidden' by the lack of appropriate data. This study has shown that domestic violence is frequent and has important social, economic and health consequences.