Comparative biology of the endocannabinoid system - Possible role in the immune response

被引：91

作者：

Salzet, M

Breton, C

Bisogno, T

Di Marzo, V

机构：

[1] Univ Sci & Technol Lille, Lab Endocrinol Annelides, CNRS, UPRESA 8017, F-59650 Villeneuve Dascq, France

[2] Arco Felice, Ist Clin Mol Interesse Biol, Naples, Italy

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 2000年 / 267卷 / 16期

关键词：

cannabinoids; anandamide; 2-arachidonoylglycerol; immune response; nitric oxide; invertebrates;

D O I：

10.1046/j.1432-1327.2000.01550.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this review we discuss data showing that the endogenous cannabinoid system, represented by cannabinoid receptors, endogenous cannabinoid receptor ligands and enzymes for the biosynthesis and degradation of these ligands, is conserved throughout evolution from coelenterates to man. This signaling system has been suggested to play several roles in animals, including the regulation of cell development and growth, nervous functions, reproduction and feeding behavior. In this article, however, we shall describe with more detail the possible function of the endogenous cannabinoid system in the modulation of immune response in organisms from the lower to the higher levels of animal evolution.

引用

收藏

页码：4917 / 4927

页数：11

相关论文

共 110 条

[21] Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages [J].

Di Marzo, V ;

Bisogno, T ;

De Petrocellis, L ;

Melck, D ;

Orlando, P ;

Wagner, JA ;

Kunos, G .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1999, 264 (01) :258-267

[22] Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells [J].

DiMarzo, V ;

DePetrocellis, L ;

Sugiura, T ;

Waku, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 227 (01) :281-288

[23] An invertebrate G-protein coupled receptor is a chimeric cannabinoid/melanocortin receptor [J].

Elphick, MR .

BRAIN RESEARCH, 1998, 780 (01) :170-173

[24] Oyster IKK-like protein shares structural and functional properties with its mammalian homologues [J].

Escoubas, JM ;

Briant, L ;

Montagnani, C ;

Hez, S ;

Devaux, C ;

Roch, P .

FEBS LETTERS, 1999, 453 (03) :293-298

[25] MAST-CELLS EXPRESS A PERIPHERAL CANNABINOID RECEPTOR WITH DIFFERENTIAL SENSITIVITY TO ANANDAMIDE AND PALMITOYLETHANOLAMIDE [J].

FACCI, L ;

DALTOSO, R ;

ROMANELLO, S ;

BURIANI, A ;

SKAPER, SD ;

LEON, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (08) :3376-3380

[26] Cannabinoid receptors and their endogenous agonists [J].

Felder, CC ;

Glass, M .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1998, 38 :179-200

[27] Cannabimimetic activity in rats and pigeons of HU 210, a potent antiemetic drug [J].

Ferrari, F ;

Ottani, A ;

Giuliani, D .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1999, 62 (01) :75-80

[28] Opiate, cannabinoid, and eicosanoid signaling converges on common intracellular pathways Nitric oxide coupling [J].

Fimiani, C ;

Liberty, T ;

Aquirre, AJ ;

Amin, I ;

Ali, N ;

Stefano, GB .

PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1999, 57 (01) :23-34

[29] Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: Coupling to nitric oxide release [J].

Fimiani, C ;

Mattocks, D ;

Cavani, F ;

Salzet, M ;

Deutsch, DG ;

Pryor, S ;

Bilfinger, TV ;

Stefano, GB .

CELLULAR SIGNALLING, 1999, 11 (03) :189-193

[30]

FRIEDMAN M, 1986, P SOC EXP BIOL MED, V182, P225

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