Triterpene glycosides from Cimicifuga racemosa

Eight new triterpene glycosides named cimiracemosides A-H, respectively, and eight known triterpene glycosides were isolated from the rhizome extracts of black cohosh (Cimicifuga racemosa). The new compounds were determined by spectral data to be 21-hydroxycimigenol-3-O-alpha-L-arabinopyranoside (1), 21-hydroxycimigenol-3-O-beta-D-xylopyranoside (2), cimigenol-3-O-alpha-L-arabinopyranoside (3), 12 beta-acetoxycimigenol-3-O-alpha-L-arabinopyranoside (4), 24-acetylisodahurinol-3-O-beta-D-xylopyrano (5), 20(S),22(R),23(S), 24(R)-16 beta:23;22:25-diepoxy-12 beta-acetoxy-3 beta,23,24-trihydroxy-9,19-cycloanost-7-ene-3-O-beta-D-xylopyranoside (6), 20(S),22(R),23(S),24(R)-16 beta:23;22:25-diepoxy-12 beta-acetoxy-3 beta,23,24-trihydroxy-9,19-cycloanost- 7-en-3-O-alpha-L-arabinopyranoside (7), and 20(S),22(R),23(S),24(R)-16 beta:23;22:25-diepoxy-12 beta-acetoxy 3 beta,23,24-trihydroxy-9,19-cycloanostane-3-O-beta-D-xylopyranoside (8).