The stressful road to antibody secretion

被引:38
作者
Ma, YJ [1 ]
Hendershot, LM [1 ]
机构
[1] St Jude Childrens Res Hosp, Dept Genet & Tumor Cell Biol, Memphis, TN 38105 USA
关键词
D O I
10.1038/ni0403-310
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Terminal B cell differentiation requires a massive increase in the biosynthetic capacity to synthesize antibodies in response to infection. New data shows the ER stress response activates and commits B cells to this robust metabolic state.
引用
收藏
页码:310 / 311
页数:3
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