Zinc-catalyzed Williamson ether synthesis in the absence of base

被引：57

作者：

Paul, S ^{[1
]}

Gupta, M ^{[1
]}

机构：

[1] Univ Jammu, Dept Chem, Jammu 180006, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 48期

关键词：

Williamson reaction; aromatic ethers; zinc powder; microwave activation; oil-bath heating;

D O I：

10.1016/j.tetlet.2004.10.009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zinc powder was found to be a highly efficient catalyst for the synthesis of aromatic ethers using microwave heating in the presence of N,N-dimethylformamide as well as under stirring in an oil-bath using tetrahydrofuran as solvent without any inorganic base. This method can be used for selective mono-, di- or tri-O-alkylations. (C) 2004 Elsevier Ltd. All rights reserved.

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收藏

页码：8825 / 8829

页数：5

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