Acylation of electrophilic olefins through decatungstate-photocatalyzed activation of aldehydes

被引：184

作者：

Esposti, Silvia

Dondi, Daniele

Fagnoni, Maurizio

Albini, Angelo

机构：

[1] Univ Pavia, Dipartimento Chim Organ, I-27100 Pavia, Italy

[2] Univ Pavia, INCA Consortium, Res Unit, I-27100 Pavia, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 14期

关键词：

acylation; aldehydes; alkenes; photochemistry; radical reactions;

D O I：

10.1002/anie.200604820

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) With tungsten and lamp: Ketones were prepared by the photocatalytic generation of acyl radicals from aldehydes and trapping them with equimolar amounts of electrophilic alkenes. Photocatalysis with tetrabutylammonium decatungstate is effective also at low temperatures (-20 to -50°C), thus minimizing radical decarbonylation and allowing acylation by highly substituted aldehydes. EWG = electron-withdrawing group. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：2531 / 2534

页数：4

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