Osmoregulation and glycerol metabolism in the yeast Saccharomyces cerevisiae

被引：102

作者：

Nevoigt, E ^{[1
]}

Stahl, U ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Biotechnol, Fachgebiet Mikrobiol & Genet, D-13355 Berlin, Germany

来源：

FEMS MICROBIOLOGY REVIEWS | 1997年 / 21卷 / 03期

关键词：

yeast; Saccharomyces cerevisiae; glycerol metabolism; osmoregulation;

D O I：

10.1111/j.1574-6976.1997.tb00352.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Glycerol is the main compatible solute in Saccharomyces cerevisiae. It is accumulated intracellularly when cells are exposed to decreased extracellular water activity. In general, increased intracellular accumulation of a solute may be caused by enhanced production, restricted dissimilation, increased retention by the plasma membrane and increased uptake from the medium. In this review, we evaluate current knowledge concerning mechanisms leading to the accumulation of glycerol in osmotically stressed cells of S. cerevisiae at the molecular and metabolic levels. An overview of glycerol metabolism in S. cerevisiae is provided.

引用

页码：231 / 241

页数：11

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