Osmoregulation and glycerol metabolism in the yeast Saccharomyces cerevisiae

被引：102

作者：

Nevoigt, E ^{[1
]}

Stahl, U ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Biotechnol, Fachgebiet Mikrobiol & Genet, D-13355 Berlin, Germany

来源：

FEMS MICROBIOLOGY REVIEWS | 1997年 / 21卷 / 03期

关键词：

yeast; Saccharomyces cerevisiae; glycerol metabolism; osmoregulation;

D O I：

10.1111/j.1574-6976.1997.tb00352.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Glycerol is the main compatible solute in Saccharomyces cerevisiae. It is accumulated intracellularly when cells are exposed to decreased extracellular water activity. In general, increased intracellular accumulation of a solute may be caused by enhanced production, restricted dissimilation, increased retention by the plasma membrane and increased uptake from the medium. In this review, we evaluate current knowledge concerning mechanisms leading to the accumulation of glycerol in osmotically stressed cells of S. cerevisiae at the molecular and metabolic levels. An overview of glycerol metabolism in S. cerevisiae is provided.

引用

页码：231 / 241

页数：11

共 68 条

[21] THE MITOCHONDRIAL RESPIRATORY-CHAIN OF YEAST - STRUCTURE AND BIOSYNTHESIS AND THE ROLE IN CELLULAR-METABOLISM [J].

DEVRIES, S ;

MARRES, CAM .

BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 895 (03) :205-239

[22]

EDGLEY M, 1983, J GEN MICROBIOL, V129, P3453

[23] CLONING AND CHARACTERIZATION OF GPD2, A 2ND GENE ENCODING SN-GLYCEROL 3-PHOSPHATE DEHYDROGENASE (NAD(+)) IN SACCHAROMYCES-CEREVISIAE, AND ITS COMPARISON WITH GPD1 [J].

ERIKSSON, P ;

ANDRE, L ;

ANSELL, R ;

BLOMBERG, A ;

ADLER, L .

MOLECULAR MICROBIOLOGY, 1995, 17 (01) :95-107

[24] GLYCEROL METABOLISM IN YEASTS - PATHWAYS OF UTILIZATION AND PRODUCTION [J].

GANCEDO, C ;

GANCEDO, JM ;

SOLS, A .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1968, 5 (02) :165-&

[25] Comparative physiology of salt tolerance in Candida tropicalis and Saccharomyces cerevisiae [J].

Garcia, MJ ;

Rios, G ;

Ali, R ;

Belles, JM ;

Serrano, R .

MICROBIOLOGY-UK, 1997, 143 :1125-1131

[26] A MECHANOSENSITIVE ION CHANNEL IN THE YEAST PLASMA-MEMBRANE [J].

GUSTIN, MC ;

ZHOU, XL ;

MARTINAC, B ;

KUNG, C .

SCIENCE, 1988, 242 (4879) :762-765

[27] MAP KINASE PATHWAYS IN YEAST - FOR MATING AND MORE [J].

HERSKOWITZ, I .

CELL, 1995, 80 (02) :187-197

[28] CLONING AND CHARACTERIZATION OF 7 CDNAS FOR HYPEROSMOLARITY-RESPONSIVE (HOR) GENES OF SACCHAROMYCES-CEREVISIAE [J].

HIRAYAMA, T ;

MAEDA, T ;

SAITO, H ;

SHINOZAKI, K .

MOLECULAR AND GENERAL GENETICS, 1995, 249 (02) :127-138

[29]

Hohmann S., 1997, YEAST STRESS RESPONS, P101

[30] LOCALIZATION OF GLYCEROL-PHOSPHATE DEHYDROGENASE IN OUTER PHASE OF MITOCHONDRIAL INNER MEMBRANE [J].

KLINGENBERG, M .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1970, 13 (02) :247-+

← 1 2 3 4 5 6 7 →