The ins and outs of ATP-dependent chromatin remodeling in budding yeast: Biophysical and proteomic perspectives

被引:37
作者
van Vugt, Joke J. F. A.
Ranes, Michael
Campsteijn, Coen
Logie, Colin
机构
[1] Radboud Univ Nijmegen, NCMLS, Dept Biol Mol, NL-6500 HB Nijmegen, Netherlands
[2] Sars Int Ctr Marine Mol Biol, N-5008 Bergen, Norway
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2007年 / 1769卷 / 03期
关键词
nucleosome; chromatin SNF2; STH1; ISW1; ISW2; INO80; SWR1; CHD1; YFR038w;
D O I
10.1016/j.bbaexp.2007.01.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ATP-dependent chromatin remodeling is performed by multi-subunit protein complexes. Over the last years, the identity of these factors has been unveiled in yeast and many parallels have been drawn with animal and plant systems, indicating that sophisticated chromatin transactions evolved prior to their divergence. Here we review current knowledge pertaining to the molecular mode of action of ATP-dependent chromatin remodeling, from single molecule studies to genome-wide genetic and proteomic studies. We focus on the budding yeast versions of SWI/SNF, RSC, DDMI, ISWI, CHD1, INO80 and SWR1. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:153 / 171
页数:19
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