A DNA nanomachine based on a duplex-triplex transition

被引:152
作者
Chen, Y [1 ]
Lee, SH [1 ]
Mao, C [1 ]
机构
[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
关键词
acidity; DNA structures; DNA; molecular devices; self-assembly;
D O I
10.1002/anie.200460789
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Making DNA work: A DNA nanomachine with a mechanism based on a DNA duplex-triplex transition (see figure) was constructed. The key component is a DNA triplex that contains C+GC triplets and is only stable under acidic conditions. The DNA machine uses H+ and OH- ions as fuel and its only waste products are H2O and NaCl.
引用
收藏
页码:5335 / 5338
页数:4
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