Prospects for functional genomics in Schizosaccharomyces pombe

被引：11

作者：

Sunnerhagen, P ^{[1
]}

机构：

[1] Univ Gothenburg, Dept Cell & Mol Biol, Lundberg Lab, S-40530 Gothenburg, Sweden

来源：

CURRENT GENETICS | 2002年 / 42卷 / 02期

关键词：

fission yeast; disruption mutations; proteomics; subcellular localisation; target identification;

D O I：

10.1007/s00294-002-0335-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学]; 090102 [作物遗传育种];

摘要：

Schizosaccharomyces pombe is well established as an experimental organism for. basic research, with well developed technologies for molecular biology, genetics and cell biology. Its full genome sequence has recently been published. Here, the prerequisites for functional genomics studies in Sch. pombe are examined and compared with those of some established prominent functional genomics model organisms, especially Saccharomyces cerevisiae. It is argued that functional genomics studies in certain areas of cellular and molecular biology could potentially be more efficiently performed in Sch. pombe than in most other experimental organisms.

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收藏

页码：73 / 84

页数：12

相关论文

共 87 条

[1]

REGULATION OF P34CDC28 TYROSINE PHOSPHORYLATION IS NOT REQUIRED FOR ENTRY INTO MITOSIS IN SACCHAROMYCES-CEREVISIAE [J].

AMON, A ;

SURANA, U ;

MUROFF, I ;

NASMYTH, K .

NATURE, 1992, 355 (6358) :368-371

[2]

Lineage-specific loss and divergence of functionally linked genes in eukaryotes [J].

Aravind, L ;

Watanabe, H ;

Lipman, DJ ;

Koonin, EV .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) :11319-11324

[3]

Bähler J, 1998, YEAST, V14, P943, DOI 10.1002/(SICI)1097-0061(199807)14:10<943::AID-YEA292>3.0.CO

[4]

2-Y

[5]

HIGH-FREQUENCY TRANSFORMATION OF THE FISSION YEAST SCHIZOSACCHAROMYCES-POMBE [J].

BEACH, D ;

NURSE, P .

NATURE, 1981, 290 (5802) :140-142

[6]

Fission yeast retrotransposon Tf1 integration is targeted to 5′ ends of open reading frames [J].

Behrens, R ;

Hayles, J ;

Nurse, P .

NUCLEIC ACIDS RESEARCH, 2000, 28 (23) :4709-4716

[7]

Genomic Exploration of the Hemiascomycetous Yeasts:: 4.: The genome of Saccharomyces cerevisiae revisited [J].

Blandin, G ;

Durrens, P ;

Tekaia, F ;

Aigle, M ;

Bolotin-Fukuhara, M ;

Bon, E ;

Casarégola, S ;

de Montigny, J ;

Gaillardin, C ;

Lépingle, A ;

Llorente, B ;

Malpertuy, A ;

Neuvéglise, C ;

Ozier-Kalogeropoulos, O ;

Perrin, A ;

Potier, S ;

Souciet, JL ;

Talla, E ;

Toffano-Nioche, C ;

Wésolowski-Louvel, M ;

Marck, C ;

Dujon, B .

FEBS LETTERS, 2000, 487 (01) :31-36

[8]

HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex [J].

Carmen, AA ;

Rundlett, SE ;

Grunstein, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (26) :15837-15844

[9]

Characterization of Schizosaccharomyces pombe Hus1:: a PCNA-related protein that associates with Rad1 and Rad9 [J].

Caspari, T ;

Dahlen, M ;

Kanter-Smoler, G ;

Lindsay, HD ;

Hofmann, K ;

Papadimitriou, K ;

Sunnerhagen, P ;

Carr, AM .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (04) :1254-1262

[10]

DELETION MUTATIONS AFFECTING AUTONOMOUSLY REPLICATING SEQUENCE ARS1 OF SACCHAROMYCES-CEREVISIAE [J].

CELNIKER, SE ;

SWEDER, K ;

SRIENC, F ;

BAILEY, JE ;

CAMPBELL, JL .

MOLECULAR AND CELLULAR BIOLOGY, 1984, 4 (11) :2455-2466

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