Biosynthesis of the dimethylallyl moiety of novobiocin via a non-mevalonate pathway

被引：30

作者：

Li, SM ^{[1
]}

Hennig, S ^{[1
]}

Heide, L ^{[1
]}

机构：

[1] Univ Tubingen, Inst Pharmazeut, D-72076 Tubingen, Germany

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 18期

关键词：

D O I：

10.1016/S0040-4039(98)00386-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

After heeding of [1-C-13]glucose to Streptomyces spheroides (NCIB 11891), the labelling pattern of the dimethylallyl moiety of novobiocin was consistent with a biosynthesis predominantly via the non-mevalonate (= pyruvate/glyceraldehyde 3-phosphate) pathway. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2717 / 2720

页数：4

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