Targeting Ions-Induced Autophagy in Cancer

被引：14

作者：

Cecconi, Francesco ^{[1
,2
]}

Jaattela, Marja ^{[3
]}

机构：

[1] Univ Roma Tor Vergata, Dept Biol, IRCCS Santa Lucia Fdn, I-00173 Rome, Italy

[2] Danish Canc Soc, Res Ctr, Unit Cell Stress & Survival, DK-2100 Copenhagen, Denmark

[3] Danish Canc Soc, Res Ctr, Unit Cell Death & Metab, DK-2100 Copenhagen, Denmark

来源：

CANCER CELL | 2014年 / 26卷 / 05期

关键词：

TUMORIGENESIS; PROMOTION; BECLIN-1;

D O I：

10.1016/j.ccell.2014.10.014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Autophagy is an important cellular homeostasis pathway, but its role in cancer remains to be fully elucidated. In this issue of Cancer Cell, Hall and colleagues describe a TRPM3-dependent autophagy pathway that is selectively important for clear cell renal cell carcinoma and can be effectively inhibited.

引用

页码：599 / 600

页数：2

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