An update on the IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design

被引：72

作者：

Califf, Robert M. ^{[1
]}

Lokhnygina, Yuliya ^{[2
]}

Cannon, Christopher P. ^{[3
]}

Stepanavage, Michael E. ^{[4
]}

McCabe, Carolyn H. ^{[3
]}

Musliner, Thomas A. ^{[5
]}

Pasternak, Richard C. ^{[5
]}

Blazing, Michael A. ^{[2
]}

Giugliano, Robert P. ^{[3
]}

Harrington, Robert A. ^{[2
]}

Braunwald, Eugene ^{[3
]}

机构：

[1] Duke Univ, Duke Translat Med Inst, Durham, NC 27706 USA

[2] Duke Univ, Duke Clin Res Inst, Durham, NC USA

[3] Brigham & Womens Hosp, TIMI Study Grp, Boston, MA 02115 USA

[4] Merck & Co Inc, Rahway, NJ 07065 USA

[5] Merck & Co Inc, N Wales, PA USA

来源：

AMERICAN HEART JOURNAL | 2010年 / 159卷 / 05期

关键词：

CARDIOVASCULAR OUTCOMES; EZETIMIBE; SIMVASTATIN; ATHEROSCLEROSIS; CANCER; NIACIN;

D O I：

10.1016/j.ahj.2010.03.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：705 / 709

页数：5

共 24 条

[1] [Anonymous], 3 NAT HEART LUNG BLO
[2] Study of Heart and Renal Protection (SHARP)
Baigent, C
Landry, M
[J]. KIDNEY INTERNATIONAL, 2003, 63 : S207 - S210
[3] Prevention and Rehabilitation - Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: The Vytorin Versus Atorvastatin (VYVA) Study
Ballantyne, CM
Abate, N
Yuan, Z
King, TR
Palmisano, J
[J]. AMERICAN HEART JOURNAL, 2005, 149 (03) : 464 - 473
[4] Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes
Cannon, Christopher P.
Giugliano, Robert P.
Blazing, Michael A.
Harrington, Robert A.
Peterson, John L.
Sisk, Christine McCrary
Strony, John
Musliner, Thomas A.
McCabe, Carolyn H.
Veltri, Enrico
Braunwald, Eugene
Califf, Robert M.
[J]. AMERICAN HEART JOURNAL, 2008, 156 (05) : 826 - 832
[5] Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy
Cannon, Christopher P.
Steinberg, Benjamin A.
Murphy, Sabina A.
Mega, Jessica L.
Braunwald, Eugene
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (03) : 438 - 445
[6] Ezetimibe and cancer - An uncertain association
Drazen, Jeffrey M.
D'Agostino, Ralph B.
Ware, James H.
Morrissey, Stephen
Curfman, Gregory D.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (13) : 1398 - 1399
[7] Rosuvastatin and Cardiovascular Events in Patients Undergoing Hemodialysis
Fellstroem, Bengt C.
Jardine, Alan G.
Schmieder, Roland E.
Holdaas, Hallvard
Bannister, Kym
Beutler, Jaap
Chae, Dong-Wan
Chevaile, Alejandro
Cobbe, Stuart M.
Groenhagen-Riska, Carola
De Lima, Jose J.
Lins, Robert
Mayer, Gert
McMahon, Alan W.
Parving, Hans-Henrik
Remuzzi, Giuseppe
Samuelsson, Ola
Sonkodi, Sandor
Sueleymanlar, Gultekin
Tsakiris, Dimitrios
Tesar, Vladimir
Todorov, Vasil
Wiecek, Andrzej
Wuethrich, Rudolf P.
Gottlow, Mattis
Johnsson, Eva
Zannad, Faiez
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (14) : 1395 - 1407
[8] Effect of Statins Alone Versus Statins Plus Ezetimibe on Carotid Atherosclerosis in Type 2 Diabetes
Fleg, Jerome L.
Mete, Mihriye
Howard, Barabara V.
Umans, Jason G.
Roman, Mary J.
Ratner, Robert E.
Silverman, Angela
Galloway, James M.
Henderson, Jeffrey A.
Weir, Matthew R.
Wilson, Charlton
Stylianou, Mario
Howard, Wm. James
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (25) : 2198 - 2205
[9] Identifying and addressing safety signals in clinical trials
Fleming, Thomas R.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (13) : 1400 - 1402
[10] Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy
Giraldez, Roberto R.
Giugliano, Robert P.
Mohanavelu, Satishkumar
Murphy, Sabina A.
McCabe, Carolyn H.
Cannon, Christopher P.
Braunwald, Eugene
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (11) : 914 - 920

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