An update on the IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design

被引:72
作者
Califf, Robert M. [1 ]
Lokhnygina, Yuliya [2 ]
Cannon, Christopher P. [3 ]
Stepanavage, Michael E. [4 ]
McCabe, Carolyn H. [3 ]
Musliner, Thomas A. [5 ]
Pasternak, Richard C. [5 ]
Blazing, Michael A. [2 ]
Giugliano, Robert P. [3 ]
Harrington, Robert A. [2 ]
Braunwald, Eugene [3 ]
机构
[1] Duke Univ, Duke Translat Med Inst, Durham, NC 27706 USA
[2] Duke Univ, Duke Clin Res Inst, Durham, NC USA
[3] Brigham & Womens Hosp, TIMI Study Grp, Boston, MA 02115 USA
[4] Merck & Co Inc, Rahway, NJ 07065 USA
[5] Merck & Co Inc, N Wales, PA USA
关键词
CARDIOVASCULAR OUTCOMES; EZETIMIBE; SIMVASTATIN; ATHEROSCLEROSIS; CANCER; NIACIN;
D O I
10.1016/j.ahj.2010.03.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:705 / 709
页数:5
相关论文
共 24 条
  • [11] Cardiovascular and metabolic risk factors: How can we improve outcomes in the high-risk patient? Discussion following Dr. Grundy's presentation
    Grundy, Scott M.
    [J]. AMERICAN JOURNAL OF MEDICINE, 2007, 120 (09) : 9 - 9
  • [12] Grundy Scott M, 2004, J Am Coll Cardiol, V44, P720, DOI 10.1016/j.jacc.2004.07.001
  • [13] Simvastatin with or without ezetimibe in familial hypercholesterolemia
    Kastelein, John J. P.
    Akdim, Fatima
    Stroes, Erik S. G.
    Zwinderman, Aeilko H.
    Bots, Michiel L.
    Stalenhoef, Anton F. H.
    Visseren, Frank L. J.
    Sijbrands, Eric J. G.
    Trip, Mieke D.
    Stein, Evan A.
    Gaudet, Daniel
    Duivenvoorden, Raphael
    Veltri, Enrico P.
    Marais, A. David
    de Groot, Eric
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (14) : 1431 - 1443
  • [14] Statin Therapy with Ezetimibe or Niacin in High-Risk Patients
    Kastelein, John J. P.
    Bots, Michiel L.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (22) : 2180 - 2183
  • [15] Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function A Randomized, Placebo-Controlled, Magnetic Resonance Imaging Study
    Lee, Justin M. S.
    Robson, Matthew D.
    Yu, Ly-Mee
    Shirodaria, Cheerag C.
    Cunnington, Colin
    Kylintireas, Ilias
    Digby, Janet E.
    Bannister, Thomas
    Handa, Ashok
    Wiesmann, Frank
    Durrington, Paul N.
    Channon, Keith M.
    Neubauer, Stefan
    Choudhury, Robin P.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (19) : 1787 - 1794
  • [16] MULTIPLE TESTING PROCEDURE FOR CLINICAL-TRIALS
    OBRIEN, PC
    FLEMING, TR
    [J]. BIOMETRICS, 1979, 35 (03) : 549 - 556
  • [17] ORIORDAN M, 2008, HEARTWIRE 0328
  • [18] Analyses of cancer data from three Ezetimibe trials
    Peto, Richard
    Emberson, Jonathan
    Landray, Martin
    Baigent, Colin
    Collins, Rory
    Clare, Robert
    Califf, Robert
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (13) : 1357 - 1366
  • [19] Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis
    Rossebo, Anne B.
    Pedersen, Terje R.
    Boman, Kurt
    Brudi, Philippe
    Chambers, John B.
    Egstrup, Kenneth
    Gerdts, Eva
    Gohlke-Barwolf, Christa
    Holme, Ingar
    Kesaniemi, Y. Antero
    Malbecq, William
    Nienaber, Christoph A.
    Ray, Simon
    Skjaerpe, Terje
    Wachtell, Kristian
    Willenheimer, Ronnie
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (13) : 1343 - 1356
  • [20] Prognostic value of the admission electrocardiogram in acute coronary syndromes
    Savonitto, S
    Ardissino, D
    Granger, CB
    Morando, G
    Prando, MD
    Mafrici, A
    Cavallini, C
    Melandri, G
    Thompson, TD
    Vahanian, A
    Ohman, EM
    Califf, RM
    Van de Werf, F
    Topol, EJ
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 281 (08): : 707 - 713