West Nile virus infection in the eastern loggerhead shrike (Lanius ludovicianus migrans):: Pathology, epidemiology, and immunization

被引:14
作者
Bertelsen, MF [1 ]
Olberg, RA
Crawshaw, GJ
Dibernardo, A
Lindsay, LR
Drebot, M
Barker, IK
机构
[1] Univ Guelph, Ontario Vet Coll, Dept Pathobiol, Guelph, ON N1G 2W1, Canada
[2] Toronto Zoo, Scarborough, ON M1B 5K7, Canada
[3] Hlth Canada, Natl Microbiol Lab, Zoonot Dis & Special Pathogens, Winnipeg, MB R3E 3R2, Canada
关键词
eastern loggerhead shrike; flaviviridae; immunization; immunohistochemistry; Lanius ludovicianus migrans; RT-PCR; West Nile virus;
D O I
10.7589/0090-3558-40.3.538
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
An outbreak of West Nile virus (WNV) infection occurred at a captive breeding facility for the endangered eastern loggerhead shrike (Lanius ludovicianus migrans) in August 2002. Within 10 d, five birds died; two were found dead, and the others died shortly after showing neurologic signs. West Nile virus was detected in all organs examined using immunohistochemistry, and its viral genome was amplified from brain and kidney samples using reverse transcription-polymerase chain reaction. None of the remaining birds in the colony had antibodies against WNV,, which suggests a mortality rate of 100%. After vaccination with a commercial equine WNV vaccine 31 of 37 (84%) of the birds had WNV neutralizing antibodies.
引用
收藏
页码:538 / 542
页数:5
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