Nanofibers Offer Alternative Ways to the Treatment of Skin Infections

被引:65
作者
Heunis, T. D. J. [1 ]
Dicks, L. M. T. [1 ]
机构
[1] Univ Stellenbosch, Dept Microbiol, ZA-7602 Stellenbosch, South Africa
来源
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY | 2010年
关键词
RESISTANT STAPHYLOCOCCUS-AUREUS; INTENSIVE-CARE-UNIT; BURN WOUND INFECTIONS; SILVER NANOPARTICLES; ELECTROSPUN NANOFIBERS; CONTROLLED-RELEASE; BIOMEDICAL APPLICATIONS; ANTIMICROBIAL ACTIVITY; POLY(ETHYLENE OXIDE); BACTERIAL BIOFILMS;
D O I
10.1155/2010/510682
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
Injury to the skin causes a breach in the protective layer surrounding the body. Many pathogens are resistant to antibiotics, rendering conventional treatment less effective. This led to the use of alternative antimicrobial compounds, such as silver ions, in skin treatment. In this review nanofibers, and the incorporation of natural antimicrobial compounds in these scaffolds, are discussed as an alternative way to control skin infections. Electrospinning as a technique to prepare nanofibers is discussed. The possibility of using these structures as drug delivery systems is investigated.
引用
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页数:10
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