Isolation of a bioactive Ca2+-mobilizing complex lipid from bovine vitreous body

被引：6

作者：

Camiña, JP

Casabiell, XA

Pérez, FR

Lage, M

Casanueva, FF

机构：

[1] Univ Santiago de Compostela, Sch Med, Dept Med, Cellular Endocrinol Lab, E-15780 Santiago De Compostela, Spain

[2] Complejo Hosp Univ Santiago, Santiago De Compostela, Spain

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1998年 / 244卷 / 03期

关键词：

D O I：

10.1006/bbrc.1998.8320

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vitreous body extracts show a potent Ca2+-mobilizing activity on fibroblast cells. This Ca2+ signal is complex, and due to the presence of two different bioactive substances. The first one was identified as acid FGF. The second one was shown to be a low molecular weight substance identified as a complex lipid by a combination of chromatographic and biochemical data. This finding raises the possibility that non-classical substances with growth factor-like activity might play a role in the regulation of proliferative processes in the eye. (C) 1998 Academic Press.

引用

页码：696 / 700

页数：5

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