Ricin, ricin agglutinin, and the ricin binding subunit structural comparison by Raman spectroscopy

被引：12

作者：

Brandt, NN

Chikishev, AY

Sotnikov, AI

Savochkina, YA

Agapov, II

Tonevitsky, AG

机构：

[1] Moscow MV Lomonosov State Univ, Ctr Int Laser, Moscow 119992, Russia

[2] Moscow MV Lomonosov State Univ, Dept Phys, Moscow 119992, Russia

[3] State Sci Ctr GNIIgenet, Moscow 113545, Russia

[4] Inst Transplantol & Artificial Organs, Moscow, Russia

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2005年 / 735卷 / SPEC. ISS.期

关键词：

Raman spectroscopy; toxins; ricin; conformation; disulfide bonds;

D O I：

10.1016/j.molstruc.2004.09.032

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Raman spectroscopy is used to study conformation-sensitive vibrational bands of the plant toxins ricin and ricin agglutinin and the ricin binding subunit in aqueous solution. The analysis of the Raman data yields the conformational state of the protein molecules differing from that predicted by the X-ray data. The differences and similarities in the conformational state of ficin. ficin agglutinin. and ficin binding subunit are discussed. (C) 2004 Elsevier B.V. All rights reserved.

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收藏

页码：293 / 298

页数：6

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