A concise asymmetric synthesis of the ADE fragment of nakadomarin

被引：72

作者：

Ahrendt, KA ^{[1
]}

Williams, RM ^{[1
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 24期

关键词：

D O I：

10.1021/ol048126e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ADE fragment of nakadomarin A has been synthesized in nine linear steps from commercial material. The key transformation is an asymmetric azomethine ylide [1,3]-dipolar cycloaddition to establish the AD-spirocyclic system containing three of the four stereocenters of the natural product.

引用

页码：4539 / 4541

页数：3

共 28 条

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